DEADLINE NOW PASSED

The position would suit a synthetic chemist with considerable analytical experience or an analytical chemist with a knowledge of synthesis.  In this position, your responsibilities will include: the synthesis and purification of libraries of linear and cyclic peptide-based compounds, using both automated peptide synthesisers and manual procedures; cleavage of peptides from resin supports; analysis by HPLC and mass spectrometry; and, modifications of peptides by enzymatic biotransformation.  You will be responsible for planning and undertaking analysis, purification, isolation and characterisation of our linear and cyclic compounds, and will need to be able to collaborate effectively with other colleagues as part of a team.

Experience with LC and LC-MS is essential, along with the ability to trouble shoot and perform routine maintenance of HPLC equipment.

A PhD in an appropriate chemical or biochemical subject would be expected, but consideration will be given to applicants who have acquired the necessary experience within industry, particularly within drug discovery.  Knowledge of the synthesis, development, purification and analysis of peptides and macrocycles would be advantageous, but is not essential.  You must be eligible to work in the UK.   Key additional attributes include:

• leading key projects to a successful conclusion;
• demonstrating the ability to communicate clearly, with good presentation and report writing skills;
• a hard working attitude, a balanced and meticulous approach to work and the ability to work well under pressure;
• to be adaptable and a team player